Colon targeted drug delivery system: A review on current approaches
نویسندگان
چکیده
منابع مشابه
Colon Targeted Drug Delivery System: a Review
Day by day there are new developments in field of colon specific drug delivery system. Colonic drug delivery has gained increased importance not just for the delivery of the drugs for the treatment of local diseases associated with the colon like Crohn’s disease, ulcerative colitis, etc. but also for the systemic delivery of proteins, therapeutic peptides, anti-asthmatic drugs, antihypertensive...
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Oral administration of different dosage forms is the most commonly used method due to greater flexibility in design of dosage form and high patient acceptance, but the gastrointestinal tract presents several formidable barriers to drug delivery. In oral colonspecific drug delivery system, colon has a large amount of lymphoma tissue (facilitates direct absorption in to the blood), negligible bru...
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Although oral delivery has a become a widely accepted route of administration of therapeutic drugs, the gastrointestinal tract presents several formidable barrier to drug delivery. The delivery of drugs to the colon has a number of therapeutic implications in the field of drug delivery. In the recent times, the colon specific drug delivery system is also gaining importance not only for local dr...
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Article reviews the research focus on potential opportunities and challenges available in new area of colon targeted drug delivery system. Colon was considered as “BLACK BOX” as, most of drugs are absorbed from upper part of GIT tract. Targeted drug delivery to the colon would ensure direct treatment at the disease site, lowering of dose and lesser systemic side effects. In addition, the colon ...
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The colon is a site where both local and systemic delivery of drugs can take place. Local delivery allows topical treatment of inflammatory bowel disease. However, treatment can be made effective if the drugs can be targeted directly into the colon, thereby reducing the systemic side effects. This review mainly describes the primary approaches for CDDS (Colon Specific Drug Delivery) namely prod...
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ژورنال
عنوان ژورنال: Indian Journal of Pharmaceutical and Biological Research
سال: 2013
ISSN: 2320-9267
DOI: 10.30750/ijpbr.1.4.24